Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Logo for

Science 289 (5479): 617-619

Copyright © 2000 by the American Association for the Advancement of Science

Dependence of Stem Cell Fate in Arabidopsis on a Feedback Loop Regulated by CLV3 Activity

Ulrike Brand,1 Jennifer C. Fletcher,2* Martin Hobe,1 Elliot M. Meyerowitz,2 Rüdiger Simon1dagger

The fate of stem cells in plant meristems is governed by directional signaling systems that are regulated by negative feedback. In Arabidopsis thaliana, the CLAVATA (CLV) genes encode the essential components of a negative, stem cell-restricting pathway. We used transgenic plants overexpressing CLV3 to show that meristem cell accumulation and fate depends directly on the level of CLV3 activity and that CLV3 signaling occurs exclusively through a CLV1/CLV2 receptor kinase complex. We also demonstrate that the CLV pathway acts by repressing the activity of the transcription factor WUSCHEL, an element of the positive, stem cell-promoting pathway.

1 Institut für Entwicklungsbiologie, Universität zu Köln, Gyrhofstrabeta e 17, D-50923 Köln, Germany.
2 Division of Biology 156-29, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA.
*   Present address: U.S. Department of Agriculture Plant Gene Expression Center, University of California Berkeley, Department of Plant and Microbial Biology, 800 Buchanan Street, Albany, CA 94710, USA.

dagger    To whom correspondence should be addressed. E-mail: ruediger.simon{at}uni-koeln.de

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Plant CLE peptides from two distinct functional classes synergistically induce division of vascular cells.
R. Whitford, A. Fernandez, R. De Groodt, E. Ortega, and P. Hilson (2008)
PNAS 105, 18625-18630
   Abstract »    Full Text »    PDF »
BAM Receptors Regulate Stem Cell Specification and Organ Development Through Complex Interactions With CLAVATA Signaling.
B. J. DeYoung and S. E. Clark (2008)
Genetics 180, 895-904
   Abstract »    Full Text »    PDF »
Non-cell-autonomous control of vascular stem cell fate by a CLE peptide/receptor system.
Y. Hirakawa, H. Shinohara, Y. Kondo, A. Inoue, I. Nakanomyo, M. Ogawa, S. Sawa, K. Ohashi-Ito, Y. Matsubayashi, and H. Fukuda (2008)
PNAS 105, 15208-15213
   Abstract »    Full Text »    PDF »
Vascular signalling mediated by ZWILLE potentiates WUSCHEL function during shoot meristem stem cell development in the Arabidopsis embryo.
M. R. Tucker, A. Hinze, E. J. Tucker, S. Takada, G. Jurgens, and T. Laux (2008)
Development 135, 2839-2843
   Abstract »    Full Text »    PDF »
Functional Diversification of CLAVATA3-Related CLE Proteins in Meristem Maintenance in Rice.
T. Suzaki, A. Yoshida, and H.-Y. Hirano (2008)
PLANT CELL 20, 2049-2058
   Abstract »    Full Text »    PDF »
Mutation of Arabidopsis BARD1 Causes Meristem Defects by Failing to Confine WUSCHEL Expression to the Organizing Center.
P. Han, Q. Li, and Y.-X. Zhu (2008)
PLANT CELL 20, 1482-1493
   Abstract »    Full Text »    PDF »
The Arabidopsis OBERON1 and OBERON2 genes encode plant homeodomain finger proteins and are required for apical meristem maintenance.
S. Saiga, C. Furumizu, R. Yokoyama, T. Kurata, S. Sato, T. Kato, S. Tabata, M. Suzuki, and Y. Komeda (2008)
Development 135, 1751-1759
   Abstract »    Full Text »    PDF »
The Receptor Kinase CORYNE of Arabidopsis Transmits the Stem Cell-Limiting Signal CLAVATA3 Independently of CLAVATA1.
R. Muller, A. Bleckmann, and R. Simon (2008)
PLANT CELL 20, 934-946
   Abstract »    Full Text »    PDF »
HD-ZIP III Activity Is Modulated by Competitive Inhibitors via a Feedback Loop in Arabidopsis Shoot Apical Meristem Development.
Y.-S. Kim, S.-G. Kim, M. Lee, I. Lee, H.-Y. Park, P. J. Seo, J.-H. Jung, E.-J. Kwon, S. W. Suh, K.-H. Paek, et al. (2008)
PLANT CELL 20, 920-933
   Abstract »    Full Text »    PDF »
REBELOTE, SQUINT, and ULTRAPETALA1 Function Redundantly in the Temporal Regulation of Floral Meristem Termination in Arabidopsis thaliana.
N. Prunet, P. Morel, A.-M. Thierry, Y. Eshed, J. L. Bowman, I. Negrutiu, and C. Trehin (2008)
PLANT CELL 20, 901-919
   Abstract »    Full Text »    PDF »
Signaling of cell fate determination by the TPD1 small protein and EMS1 receptor kinase.
G. Jia, X. Liu, H. A. Owen, and D. Zhao (2008)
PNAS 105, 2220-2225
   Abstract »    Full Text »    PDF »
From primary to secondary growth: origin and development of the vascular system.
M. Baucher, M. El Jaziri, and O. Vandeputte (2007)
J. Exp. Bot. 58, 3485-3501
   Abstract »    Full Text »    PDF »
Haploinsufficiency after successive loss of signaling reveals a role for ERECTA-family genes in Arabidopsis ovule development.
L. J. Pillitteri, S. M. Bemis, E. D. Shpak, and K. U. Torii (2007)
Development 134, 3099-3109
   Abstract »    Full Text »    PDF »
Arabidopsis JAGGED LATERAL ORGANS Is Expressed in Boundaries and Coordinates KNOX and PIN Activity.
L. Borghi, M. Bureau, and R. Simon (2007)
PLANT CELL 19, 1795-1808
   Abstract »    Full Text »    PDF »
Flowering and determinacy in Arabidopsis.
R. Sablowski (2007)
J. Exp. Bot. 58, 899-907
   Abstract »    Full Text »    PDF »
POL and PLL1 phosphatases are CLAVATA1 signaling intermediates required for Arabidopsis shoot and floral stem cells.
S.-K. Song, M. M. Lee, and S. E. Clark (2006)
Development 133, 4691-4698
   Abstract »    Full Text »    PDF »
Conservation and Diversification of Meristem Maintenance Mechanism in Oryza sativa: Function of the FLORAL ORGAN NUMBER2 Gene.
T. Suzaki, T. Toriba, M. Fujimoto, N. Tsutsumi, H. Kitano, and H.-Y. Hirano (2006)
Plant Cell Physiol. 47, 1591-1602
   Abstract »    Full Text »    PDF »
The Shoot Stem Cell Niche in Angiosperms: Expression Patterns of WUS Orthologues in Rice and Maize Imply Major Modifications in the Course of Mono- and Dicot Evolution.
J. Nardmann and W. Werr (2006)
Mol. Biol. Evol. 23, 2492-2504
   Abstract »    Full Text »    PDF »
The FLORAL ORGAN NUMBER4 Gene Encoding a Putative Ortholog of Arabidopsis CLAVATA3 Regulates Apical Meristem Size in Rice.
H. Chu, Q. Qian, W. Liang, C. Yin, H. Tan, X. Yao, Z. Yuan, J. Yang, H. Huang, D. Luo, et al. (2006)
Plant Physiology 142, 1039-1052
   Abstract »    Full Text »    PDF »
Dodeca-CLE peptides as suppressors of plant stem cell differentiation..
Y. Ito, I. Nakanomyo, H. Motose, K. Iwamoto, S. Sawa, N. Dohmae, and H. Fukuda (2006)
Science 313, 842-845
   Abstract »    Full Text »    PDF »
A plant peptide encoded by CLV3 identified by in situ MALDI-TOF MS analysis..
T. Kondo, S. Sawa, A. Kinoshita, S. Mizuno, T. Kakimoto, H. Fukuda, and Y. Sakagami (2006)
Science 313, 845-848
   Abstract »    Full Text »    PDF »
The CLAVATA3/ESR Motif of CLAVATA3 Is Functionally Independent from the Nonconserved Flanking Sequences.
M. Fiers, E. Golemiec, R. van der Schors, L. van der Geest, K. W. Li, W. J. Stiekema, and C.-M. Liu (2006)
Plant Physiology 141, 1284-1292
   Abstract »    Full Text »    PDF »
Meristems in the movies: live imaging as a tool for decoding intercellular signaling in shoot apical meristems..
F. E. Tax and A. Durbak (2006)
PLANT CELL 18, 1331-1337
   Full Text »    PDF »
Metabolic aspects of organogenesis in the shoot apical meristem.
A Fleming (2006)
J. Exp. Bot. 57, 1863-1870
   Abstract »    Full Text »    PDF »
Dynamic and Compensatory Responses of Arabidopsis Shoot and Floral Meristems to CLV3 Signaling.
R. Muller, L. Borghi, D. Kwiatkowska, P. Laufs, and R. Simon (2006)
PLANT CELL 18, 1188-1198
   Abstract »    Full Text »    PDF »
Gain-of-Function Phenotypes of Many CLAVATA3/ESR Genes, Including Four New Family Members, Correlate with Tandem Variations in the Conserved CLAVATA3/ESR Domain.
T. J. Strabala, P. J. O'Donnell, A.-M. Smit, C. Ampomah-Dwamena, E. J. Martin, N. Netzler, N. J. Nieuwenhuizen, B. D. Quinn, H. C.C. Foote, and K. R. Hudson (2006)
Plant Physiology 140, 1331-1344
   Abstract »    Full Text »    PDF »
Analysis of the Transcription Factor WUSCHEL and Its Functional Homologue in Antirrhinum Reveals a Potential Mechanism for Their Roles in Meristem Maintenance.
M. Kieffer, Y. Stern, H. Cook, E. Clerici, C. Maulbetsch, T. Laux, and B. Davies (2006)
PLANT CELL 18, 560-573
   Abstract »    Full Text »    PDF »
Control of Floral Meristem Determinacy in Petunia by MADS-Box Transcription Factors.
S. Ferrario, A. V. Shchennikova, J. Franken, R. G.H. Immink, and G. C. Angenent (2006)
Plant Physiology 140, 890-898
   Abstract »    Full Text »    PDF »
A Role for APETALA2 in Maintenance of the Stem Cell Niche.
N. A. Eckardt (2006)
PLANT CELL 18, 275-277
   Full Text »    PDF »
APETALA2 Regulates the Stem Cell Niche in the Arabidopsis Shoot Meristem.
T. Wurschum, R. Gross-Hardt, and T. Laux (2006)
PLANT CELL 18, 295-307
   Abstract »    Full Text »    PDF »
Evidence for Functional Conservation, Sufficiency, and Proteolytic Processing of the CLAVATA3 CLE Domain.
J. Ni and S. E. Clark (2006)
Plant Physiology 140, 726-733
   Abstract »    Full Text »    PDF »
Maize rough sheath2 and Its Arabidopsis Orthologue ASYMMETRIC LEAVES1 Interact with HIRA, a Predicted Histone Chaperone, to Maintain knox Gene Silencing and Determinacy during Organogenesis.
T. L. Phelps-Durr, J. Thomas, P. Vahab, and M. C.P. Timmermans (2005)
PLANT CELL 17, 2886-2898
   Abstract »    Full Text »    PDF »
Stem-Cell Homeostasis and Growth Dynamics Can Be Uncoupled in the Arabidopsis Shoot Apex.
G. V. Reddy and E. M. Meyerowitz (2005)
Science 310, 663-667
   Abstract »    Full Text »    PDF »
The 14-Amino Acid CLV3, CLE19, and CLE40 Peptides Trigger Consumption of the Root Meristem in Arabidopsis through a CLAVATA2-Dependent Pathway.
M. Fiers, E. Golemiec, J. Xu, L. van der Geest, R. Heidstra, W. Stiekema, and C.-M. Liu (2005)
PLANT CELL 17, 2542-2553
   Abstract »    Full Text »    PDF »
Overexpression of TAPETUM DETERMINANT1 Alters the Cell Fates in the Arabidopsis Carpel and Tapetum via Genetic Interaction with EXCESS MICROSPOROCYTES1/EXTRA SPOROGENOUS CELLS.
S.-L. Yang, L. Jiang, C. S. Puah, L.-F. Xie, X.-Q. Zhang, L.-Q. Chen, W.-C. Yang, and D. Ye (2005)
Plant Physiology 139, 186-191
   Abstract »    Full Text »    PDF »
Regulation of Arabidopsis shoot apical meristem and lateral organ formation by microRNA miR166g and its AtHD-ZIP target genes.
L. Williams, S. P. Grigg, M. Xie, S. Christensen, and J. C. Fletcher (2005)
Development 132, 3657-3668
   Abstract »    Full Text »    PDF »
Molecular changes associated with the setting up of secondary growth in aspen.
D. van Raemdonck, E. Pesquet, S. Cloquet, H. Beeckman, W. Boerjan, D. Goffner, M. El Jaziri, and M. Baucher (2005)
J. Exp. Bot. 56, 2211-2227
   Abstract »    Full Text »    PDF »
Regulation of WUSCHEL Transcription in the Stem Cell Niche of the Arabidopsis Shoot Meristem.
I. Baurle and T. Laux (2005)
PLANT CELL 17, 2271-2280
   Abstract »    Full Text »    PDF »
Control of Root Cap Formation by MicroRNA-Targeted Auxin Response Factors in Arabidopsis.
J.-W. Wang, L.-J. Wang, Y.-B. Mao, W.-J. Cai, H.-W. Xue, and X.-Y. Chen (2005)
PLANT CELL 17, 2204-2216
   Abstract »    Full Text »    PDF »
WUSCHEL is a primary target for transcriptional regulation by SPLAYED in dynamic control of stem cell fate in Arabidopsis.
C. S. Kwon, C. Chen, and D. Wagner (2005)
Genes & Dev. 19, 992-1003
   Abstract »    Full Text »    PDF »
Nematodes. Sophisticated Parasites of Legumes.
E. L. Davis and M. G. Mitchum (2005)
Plant Physiology 137, 1182-1188
   Full Text »    PDF »
thick tassel dwarf1 encodes a putative maize ortholog of the Arabidopsis CLAVATA1 leucine-rich repeat receptor-like kinase.
P. Bommert, C. Lunde, J. Nardmann, E. Vollbrecht, M. Running, D. Jackson, S. Hake, and W. Werr (2005)
Development 132, 1235-1245
   Abstract »    Full Text »    PDF »
ULTRAPETALA1 encodes a SAND domain putative transcriptional regulator that controls shoot and floral meristem activity in Arabidopsis.
C. C. Carles, D. Choffnes-Inada, K. Reville, K. Lertpiriyapong, and J. C. Fletcher (2005)
Development 132, 897-911
   Abstract »    Full Text »    PDF »
CORONA, a Member of the Class III Homeodomain Leucine Zipper Gene Family in Arabidopsis, Regulates Stem Cell Specification and Organogenesis.
K. A. Green, M. J. Prigge, R. B. Katzman, and S. E. Clark (2005)
PLANT CELL 17, 691-704
   Abstract »    Full Text »    PDF »
Photoperiod Regulates Flower Meristem Development in Arabidopsis thaliana.
S. Jeong and S. E. Clark (2005)
Genetics 169, 907-915
   Abstract »    Full Text »    PDF »
The gene FLORAL ORGAN NUMBER1 regulates floral meristem size in rice and encodes a leucine-rich repeat receptor kinase orthologous to Arabidopsis CLAVATA1.
T. Suzaki, M. Sato, M. Ashikari, M. Miyoshi, Y. Nagato, and H.-Y. Hirano (2004)
Development 131, 5649-5657
   Abstract »    Full Text »    PDF »
The evolution of plant development.
W. E. Friedman, R. C. Moore, and M. D. Purugganan (2004)
Am. J. Botany 91, 1726-1741
   Abstract »    Full Text »    PDF »
HANABA TARANU Is a GATA Transcription Factor That Regulates Shoot Apical Meristem and Flower Development in Arabidopsis.
Y. Zhao, L. Medrano, K. Ohashi, J. C. Fletcher, H. Yu, H. Sakai, and E. M. Meyerowitz (2004)
PLANT CELL 16, 2586-2600
   Abstract »    Full Text »    PDF »
Structural integration at the shoot apical meristem: models, measurements, and experiments.
D. Kwiatkowska (2004)
Am. J. Botany 91, 1277-1293
   Abstract »    Full Text »    PDF »
Real-time lineage analysis reveals oriented cell divisions associated with morphogenesis at the shoot apex of Arabidopsis thaliana.
G. V. Reddy, M. G. Heisler, D. W. Ehrhardt, and E. M. Meyerowitz (2004)
Development 131, 4225-4237
   Abstract »    Full Text »    PDF »
A High-Resolution Transcript Profile across the Wood-Forming Meristem of Poplar Identifies Potential Regulators of Cambial Stem Cell Identity.
J. Schrader, J. Nilsson, E. Mellerowicz, A. Berglund, P. Nilsson, M. Hertzberg, and G. Sandberg (2004)
PLANT CELL 16, 2278-2292
   Abstract »    Full Text »    PDF »
The ULTRAPETALA1 Gene Functions Early in Arabidopsis Development to Restrict Shoot Apical Meristem Activity and Acts Through WUSCHEL to Regulate Floral Meristem Determinacy.
C. C. Carles, K. Lertpiriyapong, K. Reville, and J. C. Fletcher (2004)
Genetics 167, 1893-1903
   Abstract »    Full Text »    PDF »
Genetic Regulation of Embryonic Pattern Formation.
T. Laux, T. Wurschum, and H. Breuninger (2004)
PLANT CELL 16, S190-S202
   Full Text »    PDF »
Enlarged meristems and delayed growth in plp mutants result from lack of CaaX prenyltransferases.
M. P. Running, M. Lavy, H. Sternberg, A. Galichet, W. Gruissem, S. Hake, N. Ori, and S. Yalovsky (2004)
PNAS 101, 7815-7820
   Abstract »    Full Text »    PDF »
Surface growth at the reproductive shoot apex of Arabidopsis thaliana pin-formed 1 and wild type.
D. Kwiatkowska (2004)
J. Exp. Bot. 55, 1021-1032
   Abstract »    Full Text »    PDF »
Genome-Wide Analysis of Spatial Gene Expression in Arabidopsis Flowers.
F. Wellmer, J. L. Riechmann, M. Alves-Ferreira, and E. M. Meyerowitz (2004)
PLANT CELL 16, 1314-1326
   Abstract »    Full Text »    PDF »
Comparative Analysis of the Receptor-Like Kinase Family in Arabidopsis and Rice.
S.-H. Shiu, W. M. Karlowski, R. Pan, Y.-H. Tzeng, K. F. X. Mayer, and W.-H. Li (2004)
PLANT CELL 16, 1220-1234
   Abstract »    Full Text »    PDF »
The Arabidopsis JAGGED gene encodes a zinc finger protein that promotes leaf tissue development.
C. K. Ohno, G. V. Reddy, M. G. B. Heisler, and E. M. Meyerowitz (2004)
Development 131, 1111-1122
   Abstract »    Full Text »    PDF »
MGOUN3, an Arabidopsis gene with TetratricoPeptide-Repeat-related motifs, regulates meristem cellular organization.
S. Guyomarc'h, T. Vernoux, J. Traas, D.-X. Zhou, and M. Delarue (2004)
J. Exp. Bot. 55, 673-684
   Abstract »    Full Text »    PDF »
WUSCHEL induces shoot stem cell activity and developmental plasticity in the root meristem.
J.-L. Gallois, F. R. Nora, Y. Mizukami, and R. Sablowski (2004)
Genes & Dev. 18, 375-380
   Abstract »    Full Text »    PDF »
LRR-containing receptors regulating plant development and defense.
A. Dievart and S. E. Clark (2004)
Development 131, 251-261
   Abstract »    Full Text »    PDF »
An Invertase Inhibitor from Maize Localizes to the Embryo Surrounding Region during Early Kernel Development.
N. J. Bate, X. Niu, Y. Wang, K. S. Reimann, and T. G. Helentjaris (2004)
Plant Physiology 134, 246-254
   Abstract »    Full Text »    PDF »
Microsurgical and laser ablation analysis of interactions between the zones and layers of the tomato shoot apical meristem.
D. Reinhardt, M. Frenz, T. Mandel, and C. Kuhlemeier (2003)
Development 130, 4073-4083
   Abstract »    Full Text »    PDF »
Stem cell homeostasis in the Arabidopsis shoot meristem is regulated by intercellular movement of CLAVATA3 and its sequestration by CLAVATA1.
M. Lenhard and T. Laux (2003)
Development 130, 3163-3173
   Abstract »    Full Text »    PDF »
Expansion of the Receptor-Like Kinase/Pelle Gene Family and Receptor-Like Proteins in Arabidopsis.
S.-H. Shiu and A. B. Bleecker (2003)
Plant Physiology 132, 530-543
   Abstract »    Full Text »    PDF »
Stem cell regulation in the shoot meristem.
R. Gross-Hardt and T. Laux (2003)
J. Cell Sci. 116, 1659-1666
   Abstract »    Full Text »    PDF »
The SHOOTLESS2 and SHOOTLESS1 Genes Are Involved in Both Initiation and Maintenance of the Shoot Apical Meristem Through Regulating the Number of Indeterminate Cells.
N. Satoh, J.-I. Itoh, and Y. Nagato (2003)
Genetics 164, 335-346
   Abstract »    Full Text »    PDF »
Dominant-Negative Receptor Uncovers Redundancy in the Arabidopsis ERECTA Leucine-Rich Repeat Receptor-Like Kinase Signaling Pathway That Regulates Organ Shape.
E. D. Shpak, M. B. Lakeman, and K. U. Torii (2003)
PLANT CELL 15, 1095-1110
   Abstract »    Full Text »
CLAVATA1 Dominant-Negative Alleles Reveal Functional Overlap between Multiple Receptor Kinases That Regulate Meristem and Organ Development.
A. Dievart, M. Dalal, F. E. Tax, A. D. Lacey, A. Huttly, J. Li, and S. E. Clark (2003)
PLANT CELL 15, 1198-1211
   Abstract »    Full Text »
Molecular Population Genetics of the Arabidopsis CLAVATA2 Region: The Genomic Scale of Variation and Selection in a Selfing Species.
K. A. Shepard and M. D. Purugganan (2003)
Genetics 163, 1083-1095
   Abstract »    Full Text »    PDF »
DRL1, a Homolog of the Yeast TOT4/KTI12 Protein, Has a Function in Meristem Activity and Organ Growth in Plants.
H. Nelissen, J. H. Clarke, M. De Block, S. De Block, R. Vanderhaeghen, R. E. Zielinski, T. Dyer, S. Lust, D. Inze, and M. Van Lijsebettens (2003)
PLANT CELL 15, 639-654
   Abstract »    Full Text »    PDF »
The DORNROSCHEN/ENHANCER OF SHOOT REGENERATION1 Gene of Arabidopsis Acts in the Control of Meristem Cell Fate and Lateral Organ Development.
T. Kirch, R. Simon, M. Grunewald, and W. Werr (2003)
PLANT CELL 15, 694-705
   Abstract »    Full Text »    PDF »
Shoot meristem maintenance is controlled by a GRAS-gene mediated signal from differentiating cells.
J. Stuurman, F. Jaggi, and C. Kuhlemeier (2002)
Genes & Dev. 16, 2213-2218
   Abstract »    Full Text »    PDF »
Regulation of CLV3 Expression by Two Homeobox Genes in Arabidopsis.
U. Brand, M. Grunewald, M. Hobe, and R. Simon (2002)
Plant Physiology 129, 565-575
   Abstract »    Full Text »    PDF »
The Lateral Organ Boundaries Gene Defines a Novel, Plant-Specific Gene Family.
B. Shuai, C. G. Reynaga-Pena, and P. S. Springer (2002)
Plant Physiology 129, 747-761
   Abstract »    Full Text »    PDF »
WUSCHEL signaling functions in interregional communication during Arabidopsis ovule development.
R. Gro{beta}-Hardt, M. Lenhard, and T. Laux (2002)
Genes & Dev. 16, 1129-1138
   Abstract »    Full Text »    PDF »
Maintenance of Shoot and Floral Meristem Cell Proliferation and Fate.
V. K. Sharma and J. C. Fletcher (2002)
Plant Physiology 129, 31-39
   Full Text »    PDF »
CLV3 Is Localized to the Extracellular Space, Where It Activates the Arabidopsis CLAVATA Stem Cell Signaling Pathway.
E. Rojo, V. K. Sharma, V. Kovaleva, N. V. Raikhel, and J. C. Fletcher (2002)
PLANT CELL 14, 969-977
   Abstract »    Full Text »    PDF »
Brassinosteroids and Plant Steroid Hormone Signaling.
G. J. Bishop and C. Koncz (2002)
PLANT CELL 14, S97-110
   Full Text »    PDF »
Signaling In and Out: Control of Cell Division and Differentiation in the Shoot and Root.
K. Nakajima and P. N. Benfey (2002)
PLANT CELL 14, S265-276
   Full Text »    PDF »
Signalling in Plant Lateral Organ Development.
J. F. Golz and A. Hudson (2002)
PLANT CELL 14, S277-288
   Full Text »    PDF »
Plasmodesmata: Pathways for Protein and Ribonucleoprotein Signaling.
V. Haywood, F. Kragler, and W. J. Lucas (2002)
PLANT CELL 14, S303-325
   Full Text »    PDF »
Combined SHOOT MERISTEMLESS and WUSCHEL trigger ectopic organogenesis in Arabidopsis.
J.-L. Gallois, C. Woodward, G. V. Reddy, and R. Sablowski (2002)
Development 129, 3207-3217
   Abstract »    Full Text »    PDF »
Plant Receptor-Like Kinase Gene Family: Diversity, Function, and Signaling.
S.-H. Shiu and A. B. Bleecker (2001)
Sci. STKE 2001, re22
   Abstract »    Full Text »    PDF »
Diversity of Arabidopsis Genes Encoding Precursors for Phytosulfokine, a Peptide Growth Factor.
H. Yang, Y. Matsubayashi, K. Nakamura, and Y. Sakagami (2001)
Plant Physiology 127, 842-851
   Abstract »    Full Text »    PDF »
The fasciated ear2 gene encodes a leucine-rich repeat receptor-like protein that regulates shoot meristem proliferation in maize.
F. Taguchi-Shiobara, Z. Yuan, S. Hake, and D. Jackson (2001)
Genes & Dev. 15, 2755-2766
   Abstract »    Full Text »    PDF »
Extracellular Calmodulin Stimulates Light-Independent RbcS-GUS Expression in Suspension-Cultured Cells of Transgenic Tobacco.
J. Zhou, L. Ma, S. Zhang, Y. Zhu, and D. Sun (2001)
Plant Cell Physiol. 42, 1049-1055
   Abstract »    Full Text »    PDF »
The Maize CRINKLY4 Receptor Kinase Controls a Cell-Autonomous Differentiation Response.
P. W. Becraft, S.-H. Kang, and S.-G. Suh (2001)
Plant Physiology 127, 486-496
   Abstract »