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In the Current Issue 25 November 2008 (Issue 47)


Editors' Choice

Making a Tight Seal
J. M. Stenman et al., Science 322, 1247-1250 (2008).
E. Lammert, Science 322, 1195-1196 (2008).
Summary

plus...

Editorial Guide

How to "Cell" a Genomic or Proteomic Screen
Michael B. Yaffe
Abstract  |  Full Text  |  PDF

Research

Identification of ROCK1 as an Upstream Activator of the JIP-3 to JNK Signaling Axis in Response to UVB Damage
Pat P. Ongusaha, Hank H. Qi, Lakshmi Raj, Young-Bum Kim, Stuart A. Aaronson, Roger J. Davis, Yang Shi, James K. Liao, Sam W. Lee
Editor's Summary  |  Abstract  |  Full Text  |  PDF  |  Supplementary Materials

γ-Secretase Limits the Inflammatory Response Through the Processing of LRP1
Kai Zurhove, Chikako Nakajima, Joachim Herz, Hans H. Bock, Petra May
Editor's Summary  |  Abstract  |  Full Text  |  PDF  |  Supplementary Materials

Perspectives

An All-Purpose Tool for Axon Guidance
Leslayann C. Schecterson and Mark Bothwell
Abstract  |  Full Text  |  PDF

Dynein-Independent Functions of DYNLL1/LC8: Redox State Sensing and Transcriptional Control
Stephen M. King
Abstract  |  Full Text  |  PDF  |  Interactive Figure

Podcast

Science Signaling Podcast: 25 November 2008
Petra May and Annalisa M. VanHook
Abstract  |  Full Text |  Podcast

In Literature

What's Hot
Read this highly accessed article published recently in a previous issue: Nedd4 Controls Animal Growth by Regulating IGF-1 Signaling Abstract  |  Full Text
Virtual Journal
Check out this article, just added to the Virtual Journal: Myc Inhibits p27-Induced Erythroid Differentiation of Leukemia Cells by Repressing Erythroid Master Genes without Reversing p27-Mediated Cell Cycle Arrest Abstract  |  Full Text  |  Search and browse the Virtual Journal
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In Community

Events, Meeting Reports, and Presentations
Check out the calendar, read highlights, and view presentations of cell signaling meetings and conferences.
Directory
Featured person: Craig A Doupnik. Find collaborators and people with shared research interests—join the Signaling community and add your information to the Directory!
Forums
Share highlights from signaling meetings, read the highlights from the Annual Meeting of the Society for Developmental Biology in the Open Forum on Cell Signaling.
E-Letters
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In Resources

Teaching Resources
More than 50 different resources provide information for course planning, lecture notes, slides, and animations.
Glossary
Find out what those acronyms and abbreviations mean. Browse or search the glossary of cell signaling terms. Look at the list of the most recently added terms.
Podcasts
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ST NetWatch
Featured in Bioinformatics Resources: SenseLab. Explore the sites selected by the editors or submit your favorite signal transduction Web site.
Funding Sources
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Jobs
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Selected Japanese translations
by COSMO BIO

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Science Signaling. ISSN 1937-9145 (pre-2008: Science's STKE. ISSN 1525-8882)